Head and Neck Surgery in Oncologic Patients: Laryngectomy and Radial Neck Dissection

  • Pamela Amakwe UzoigweEmail author
  • Maxie Pollard
  • Ursula Uduak Williams
Reference work entry


Laryngeal cancer is the second most common form of head and neck cancer. The main objective of a laryngectomy is to achieve a cancer cure; however, maintaining good speech and swallow functions is very critical to the patient’s quality of life. While laryngeal preservation is preferred, at times the best oncological and functional outcome might involve removing the entire larynx.

Depending on the extent of involvement, a total or partial laryngectomy might be performed. Sometimes if there is regional metastasis to the surrounding lymph node, a radical neck dissection can be performed as well. Although there has been a steady decline in laryngeal cancers related to alcohol and tobacco abuse, the increase in human papillomavirus infection has caused a steady increase in the United States and other western countries. Radical neck dissection is indicated when there is an involvement of the sternocleidomastoid muscle, internal jugular vein, or spinal accessory nerve and cervical lymph nodes. The perioperative care of patients undergoing either a partial/total laryngectomy or a radical neck dissection requires adequate planning and knowledge of each step of the perioperative phase.


Larynx Total laryngectomy Radical neck dissection Laryngeal carcinoma Oropharynx Laryngopharynx Partial laryngectomy 


  1. 1.
    Bailey B, Johnson J, Newlands S. Head and neck surgery otolaryngology, vol. 2. 4th ed. Philadelphia: Lippincott Williams and Wilkins; 1998.Google Scholar
  2. 2.
    Cyrus K, Manolis H. Prevention of complication in neck dissection. Head Neck Oncol. 2009;1:35.CrossRefGoogle Scholar
  3. 3.
    Ercan P, Abdulkadir I, Caglar C. Supracricoid partial laryngectomy: analyses of oncologic and functional outcome: otolaryngology-head and neck. Sage Journals 2012.
  4. 4.
    Gino M, Rosario M, Giuseppe C, Fortunata M, Staffieri A. Current opinion in diagnosis and treatment of laryngeal carcinoma. Cancer Treat Rev. 2006;32:504–15. Scholar
  5. 5.
    Maurizi M, Almadari G, Ferrandina G, Distefani M, Romanini M, Cadoni, Paludetti G, Scambia G, Mancuso. Prognostic significance of epidermal growth factor receptor in laryngeal squamous cell carcinoma. Br J Cancer. 1996;74:1253–7.CrossRefGoogle Scholar
  6. 6.
    MacLachclan, Ferson D, Pytynia K, Diaz E, Nguyen N, Botnick W. Perioperative care of patients with head and neck cancer.Google Scholar
  7. 7.
    Naveed B, Eadaiun C, Gerard L, Patrick S. Hypocalcemia after total laryngectomy. Laryngoscope. 2013;124:1128–33.Google Scholar
  8. 8.
    Pasha R, Golub J. Otolaryngology head and neck surgery: Clinical references guide, 4th ed. Plural publishing; 2014.Google Scholar
  9. 9.
    Herman R. Staging of laryngeal and hypopharyngeal cancer: value of imaging studies. Eur Radiol. 2006;16:2386–400.CrossRefGoogle Scholar
  10. 10.
    Scott W, Cobb R, Pang L. Post-operative wound infection in salvage laryngectomy: does antibiotics prophylaxis have an impact? Eur Arch Otorhinolarngol. 2012;269:2415–22.CrossRefGoogle Scholar
  11. 11.
    Shanthi M, Forastiere AA. Head and neck squamous cell carcinoma: update on epidemiology, diagnosis, and treatment. Symp Neoplastic Hematol Med Oncol. 2016;91(3):386–96.Google Scholar
  12. 12.
    Prakash S, Rapsang A, Kumar S, Bhatia A. Postoperative hypertension following radical neck dissection. J Anesthesiol Clin Pharmacol. 2012;28(1):121–3.CrossRefGoogle Scholar
  13. 13.
    Sophia N, Jihane B, Mohammed, Chihab M, Rkain I, Jalila B, Mohammed B, Abdelillah Q, Essakalli L. Evaluation of post laryngectomy pharyngocutaneous fistula risk factors. Iran J Otorhi. 2016;28(2).Google Scholar
  14. 14.
    Sternson KM, Brockstein B, Ross M. Epidemiology and risk factors for head and neck cancer. 2018.
  15. 15.
    Zbairen P, Becker M, Liang H. Staging of laryngeal cancer: endoscopy, computed tomography and magnetic resonance versus histopathology. Eur Arch Otorhinolaryngol. 1997;254:117–22.CrossRefGoogle Scholar
  16. 16.
    Zhoa, Jin T, Wang HG. Treatment and prognosis of patients with recurrent laryngeal carcinoma: a retrospective study. Head Neck Oncol. 2015;5(2):10.Google Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Pamela Amakwe Uzoigwe
    • 1
    Email author
  • Maxie Pollard
    • 1
  • Ursula Uduak Williams
    • 1
  1. 1.UT MD Anderson Cancer CenterHoustonUSA

Section editors and affiliations

  • Garry Brydges
    • 1
  1. 1.Department of Anesthesiology Division of Anesthesia, Critical Care and Pain MedicineThe University of Texas MD Anderson Cancer CenterHoustonUSA

Personalised recommendations