Management of Multidrug-Resistant Enterobacteriaceae in Critically Ill Cancer Patients

  • Juan David PlataEmail author
  • Ximena Castañeda
Reference work entry


Multidrug-resistant bacterial infections in critical ill cancer patients has become a trending problem in the last years because of the challenge provided in treatment, of the limited tools in our disposal, and of the high mortality associated in these infections. This has also led to an increase in hospital expenses, and by 2050, it is predicted that the problem will reach excruciating instances with incredible high costs and a mortality higher than other diseases like stroke or diabetes mellitus complications.

It is important to provide strategies pharmacological and nonpharmacological for the success in the treatment of these infections and to prevent the dissemination of life-threatening pathogens before they overcome our available antibiotics.

The following chapter discusses the importance of multidrug-resistant Enterobacteriaceae, how resistance develops, epidemiology, definitions of multidrug resistance, and diverse strategies to treat these bacteria according to its acquired resistance from Ampc and ESBL to carbapenem-resistant Enterobacteriaceae.


Enterobacteriaceae Multidrug resistance Beta-lactamase Carbapenemase Pandrug resistant 


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.School of Medicine and Health SciencesMeDeri University HospitalBogotáColombia
  2. 2.Los Cobos Medical CenterBogotáColombia
  3. 3.Rosario UniversityBogotáColombia

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