The normal anatomy and physiology of the periodontium is well known to dentists and dental specialists, as are the effects on the periodontium of plaque-associated bacterial infections. However, the gingivae may be involved in many other local and systemic conditions. The purpose of this chapter is to describe some of the less common pathological conditions that may affect one or more of the components of the periodontium and to discuss how clinicians can ensure these lesions are diagnosed and managed in a timely manner.
KeywordsGingival lesions Periodontium Periodontal diseases and conditions Non-plaque gingival pathology Immunological Lichen planus Infectious Drug-induced Leukoplakia Erythroplakia Neoplastic
- Akrish S, Ben-Izhak OF, Sabo E, Rachmiel A. Oral squamous cell carcinoma associated with proliferative verrucous leukoplakia compared with conventional squamous cell carcinoma-a clinical, histologic and immunohistochemical study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2015;119:318–25.CrossRefGoogle Scholar
- Brown AL, Camargo de Moraes P, Sperandio M, Borges Soares A, Cavalcanti Araújo V, Passador-Santos F. Peripheral giant cell granuloma associated with a dental implant: a case report and review of the literature. Case Rep Dent. 2015;2015:697673. https://doi.org/10.1155/2015/697673.CrossRefPubMedPubMedCentralGoogle Scholar
- Caton JG, Armitage G, Berglundh T, Chapple ILC, Jepsen S, Kornman KS, et al. A new classification scheme for periodontal and peri-implant diseases and conditions - Introduction and key changes from the 1999 classification. J Periodontol. 2018;89 (1 Suppl):S1–S8. https://doi.org/10.1002/JPER.18-0157.PubMedPubMedCentralCrossRefGoogle Scholar
- Chan ES, Thornhill M, Zakrzewska J. Interventions for treating oral lichen planus. J Cochrane Database Syst Rev. 2000;2:CD001168.Google Scholar
- Kujan O, Al-Shawaf AZ, Azzeghaiby S, AlManadille A, Aziz K, Raheel SA. Immunohistochemical comparison of p53, Ki-67, CD68, vimentin, α-smooth muscle actin and alpha-1-antichymotrypsin in oral peripheral and central giant cell granuloma. J Contemp Dent Pract. 2015;16:20–4.PubMedCrossRefGoogle Scholar
- Silva TDB, Ferreira CBT, Leite GB, Pontes JRdM, Antunes HS. Oral manifestations of lymphoma: a systemic review. Ecancermedicalscience. 2016;10. https://doi.org/10.3332/ecancer.2016.665.
- Thongprasom K, Carrozzo M, Furness S, Lodi G. Interventions for treating oral lichen planus. Cochrane Database Syst Rev. 2011. https://doi.org/10.1002/14651858.CD001168.pub2.
- Vered M, Muller S, Heikinheimo K. Ameloblastoma, extraosseous/peripheral type. In: El-Nagger AK, Chan JKC, Grandid JR, Takata T, Slootweg PJ, editors. WHO classification of head and neck tumours. Lyon, France: International Agency for Research on Cancer (IARC); 2017. p. 218.Google Scholar