Atopy as a Factor in the Prognosis of Hand Dermatitis

  • Birgitta MedingEmail author
Reference work entry


The 1-year period prevalence of hand eczema is about 10% in adults in the general population. More females than males are affected and the disease is most frequent at young ages. These differences in prevalence are mainly considered to be related to differences in skin irritant exposure. The origin of hand eczema is often multifactorial, with exogenous and endogenous factors contributing. Hand eczema has an unfavorable prognosis. Persistent symptoms are found in a large proportion of individuals with hand eczema in follow-up studies. The condition tends to have a chronic, often relapsing, course. Atopic dermatitis is a major risk factor for hand eczema. At least half of the people with moderate to severe atopic dermatitis in childhood have hand eczema as adults. In population-based studies, a threefold higher prevalence of hand eczema is usually found among people with atopy than people without. Atopy is found to have a negative influence on the prognosis of hand eczema in most follow-up studies. This applies to hand eczema cohorts from the general population, patients from dermatology clinics, and patients with occupational skin disease.


Clearing Consequences Follow-up Hand eczema Improvement Persistence Severity 


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Institute of Environmental MedicineKarolinska InstitutetStockholmSweden

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