List of Discussed NF-κB Family Members and Regulatory Molecules
NFκB1: p105, p50, KBF1, EBP-1
RelA: p65, NFKB3
RelB: I-REL
REL: c-Rel
NFκB2: p100, p52; LYT10
Bcl-3: BCL4, D19S37
NFKBIA: IκBα, IKBA, MAD-3, NFKBI
NFKBIB: IκBβ, IKBB, TRIP9
NFKBIE: IκBε, IKBE
NFKBIZ: IκBζ, IKBZ, INAP, MAIL
CHUK: IKKα, IKBKA, IKK1, IKKA, NFKBIKA, TCF16
IKBKB: IKKβ, IKK2, IKKB, NFKBIKB
IKBKG: IKKγ, NEMO, AMCBX1, FIP-3, FIP3, Fip3p, IP, IP1, IP2, IPD2, IKKAP1, IKKG
IKBKE: IKKε, IKKE, IKKI
MAP3K14: NIK, HS, HSNIK
TNFAIP3: A20, OTUD7C, TNFA1P2
OTUD7B: CEZANNE
CYLD: HSPC057, CDMT, CYLD1, CYLDI, EAC, MFT1, SBS, TEM, USPL2
Historical Background: Discovery and Structure
NF-κB (nuclear factor-kappa-light-chain-enhancer of activated B cells) is a collective term for a family of transcription factors. NF-κB has a complex regulation, modulates the expression of a wide set of genes, both by promoting and by suppressing...
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Valiño-Rivas, L., Gonzalez-Lafuente, L., Sanz, A.B., Poveda, J., Ortiz, A., Sanchez-Niño, M.D. (2018). NF-κB Family. In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, Cham. https://doi.org/10.1007/978-3-319-67199-4_220
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