Skip to main content

GCAP (Guanylate Cyclase–Activating Protein)

  • Reference work entry
  • First Online:
Book cover Encyclopedia of Signaling Molecules
  • 75 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 4,499.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 4,499.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Behnen P, Dell’Orco D, Koch KW. Involvement of the calcium sensor GCAP1 in hereditary cone dystrophies. Biol Chem. 2010;391:631–7.

    Article  PubMed  CAS  Google Scholar 

  • Burgoyne RD. Neuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signaling. Nat Rev Neurosci. 2007;8:182–93.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Dizhoor AM, Olshevskaya EV, Peshenko IV. Mg2+/Ca2+ cation binding cycle of guanylyl cylase activating proteins (GCAPs): role in regulation of photoreceptor guanylyl cyclase. Mol Cell Biochem. 2010;334:117–24.

    Article  PubMed  CAS  Google Scholar 

  • Fain GL, Matthews HR, Cornwall C, Koutalos Y. Adaptation in vertebrate photoreceptors. Physiol Rev. 2001;81:117–51.

    Article  PubMed  CAS  Google Scholar 

  • Imanishi Y, Yang L, Sokal I, Filipek S, Palczewski K, Baehr W. Diversity of guanylate cyclase-activating proteins (GCAPs) in teleost fish: characterization of three novel GCAPs (GCAP4, GCAP5, GCAP7) from zebrafish (Danio rerio) and prediction of eight GCAPs (GCAP1-8) in pufferfish (Fugu rubripes). J Mol Evol. 2004;59:204–17.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Koch KW, Dell’Orco D. A calcium relay mechanism in vertebrate phototransduction. ACS Chem Neurosci. 2013;4:909–17.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Koch KW, Stryer L. Highly cooperative feedback control of retinal rod guanylate cyclase by calcium ions. Nature. 1988;334:64–6.

    Article  PubMed  CAS  Google Scholar 

  • Koch KW, Duda T, Sharma RK. Ca2+-modulated vision-linked ROS-GC guanylate cyclase transduction machinery. Mol Cell Biochem. 2010;334:105–15.

    Article  PubMed  CAS  Google Scholar 

  • Luo DG, Xue T, Yau KW. How vision begins: an odyssey. Proc Natl Acad Sci USA. 2008;105:9855–62.

    Article  PubMed  PubMed Central  Google Scholar 

  • Rätscho N, Scholten A, Koch KW. Expression profiles of three novel sensory guanylate cyclases and guanylate cyclase-activating proteins in the zebrafish retina. Biochim Biophys Acta. 2009;1793:1110–4.

    Article  PubMed  CAS  Google Scholar 

  • Rätscho N, Scholten A, Koch KW. Diversity of guanylate cyclases in teleost fishes. Mol Cell Biochem. 2010;334:207–14.

    Article  PubMed  CAS  Google Scholar 

  • Stephen R, Bereta G, Golczak M, Palczewski K, Sousa MC. Stabilizing function for myristoyl group revealed by the crystal structure of a neuronal calcium sensor, guanylate cyclase-activating protein 1. Sturcture. 2007;15:1392–402.

    Article  CAS  Google Scholar 

  • Stephen R, Filipek S, Palczewski K, Sousa MC. Ca2+-dependent regulation of phototransduction. Photochem Photobiol. 2008;84:903–10.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Takemoto N, Tachibanaki S, Kawamura S. High cGMP synthetic activity in carp cones. Proc Natl Acad Sci USA. 2009;106:11788–93.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Karl-Wilhelm Koch .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Koch, KW. (2018). GCAP (Guanylate Cyclase–Activating Protein). In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, Cham. https://doi.org/10.1007/978-3-319-67199-4_12

Download citation

Publish with us

Policies and ethics