Skip to main content

Heat Shock Protein (HSP)

  • Reference work entry
  • First Online:
Book cover Encyclopedia of Signaling Molecules

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 4,499.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 4,499.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Brown IR. Heat shock proteins and neurodegenerative diseases. In: Calderwood SK, editor. Cell stress proteins. 7th ed. New York: Springer; 2007. p. 396–421.

    Chapter  Google Scholar 

  • Calderwood SK, Khaleque A, Sawyer DB, Ciocca DR. Heat shock proteins in cancer: chaperones of tumorigenesis. Trends Biochem Sci. 2006;31(3):164–72.

    Article  PubMed  CAS  Google Scholar 

  • Fernandes M, O’Brien T, Lis JT. Structure and regulation of heat shock gene promoters. Cold Spring Harb Lab Press. 1994;26:375–93.

    CAS  Google Scholar 

  • Georgopoulos CP. Bacterial mutants in which the gene N function of bacteriophage lambda is blocked have an altered RNA polymerase. PNAS. 1971;68:2977–81.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Grune T, Catalgol B, Licht A, Ermak G, Pickering A, Ngo JK, et al. HSP70 mediates dissociation and reassociation of the 26S proteasome during adaptation to oxidative stress. Free Radic Biol Med. 2011;51(7):1355–64.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Hilton GR, Lioe H, Stengel F, Baldwin AJ, Benesch JLP. Small heat-shock proteins: paramedics of the cell. In: Jackson SE, editor. Molecular chaperons. Heidelberg: Springer; 2013. p. 69–98.

    Google Scholar 

  • Jackson SE. Hsp90: structure and function. In: Jackson SE, editor. Molecular chaperons. Heidelberg: Springer; 2013. p. 155–240.

    Chapter  Google Scholar 

  • Jakob U, Gaestel M, Engel K, Buchner J. Small heat shock proteins are molecular chaperons. J Biol Chem. 1993;268(3):1517–20.

    PubMed  CAS  Google Scholar 

  • Kampinga HH, Craig EA. The HSP70 chaperone machinery: J proteins as drivers of functional specificity. Nat Rev Mol Cell Biol. 2010;11(8):579–92.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Kampinga HH, Hageman J, Vos MJ, Kubota H, Tanguay RM, Bruford EA, et al. Guidelines for the nomenclature of the human heat shock proteins. Cell Stress Chaperones. 2009;14(1):105–11.

    Article  PubMed  CAS  Google Scholar 

  • Koninkx JF. Protein synthesis in salivary glands of Drosophila hydei after experimental gene induction. Biochem J. 1976;158(3):623–8.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Li J, Buchner J. Structure, function and regulation of the Hsp90 machinery. Biomed J. 2013;36(3):106–17.

    Article  PubMed  Google Scholar 

  • Lis J, Wu C. Protein traffic on the heat shock promoter: parking, stalling and trucking alone. Cell. 1993;74:1–4.

    Article  PubMed  CAS  Google Scholar 

  • Mayer MP, Bukau B. Hsp70 chaperones: cellular functions and molecular mechanism. Cell Mol Life Sci. 2005;62(6):670–84.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Morimoto RI. Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators. Genes Dev. 1998;12:3788–96.

    Article  PubMed  CAS  Google Scholar 

  • Oh HJ, Easton D, Murawski M, Kaneko Y, Subjeck JR. The chaperoning activity of hsp110: identification of functional domains by use of targeted deletions. J Biol Chem. 1999;274(22):15712–8.

    Article  PubMed  CAS  Google Scholar 

  • Qiu XB, Shao YM, Miao S, Wang L. The diversity of the DnaJ/Hsp40 family, the crucial partners for Hsp70 chaperones. Cell Mol Life Sci. 2006;63(1):2560–70.

    Article  PubMed  CAS  Google Scholar 

  • Ranson NA, White HE, Saibil HR. Chaperonins. Biochem J. 1998;333(1):233–42.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Ritossa F. A new puffing pattern induced by temperature shock and DNP in drosophila. Experientia. 1962;18(12):571–3.

    Article  CAS  Google Scholar 

  • Sauk JJ, Nikitakis N, Siavash H. Hsp47 a novel collagen binding serpin chaperone, autoantigen and therapeutic target. Front Biosci. 2005;10:107–118.

    Article  PubMed  CAS  Google Scholar 

  • Shaner L, Gibney PA, Morano KA. The Hsp110 protein chaperone Sse1 is required for yeast cell wall integrity and morphogenesis. Curr Genet. 2008;54(1):1–11.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Valpuesta JM, Matin-Benito J, Gomez-Puertas P, Carroscosa JL, Willison KR. Structure and function of a protein folding machine: the eukaryotic cytosolic chaperonin CCT. FEBS Lett. 2002;529(1):11–6.

    Article  PubMed  CAS  Google Scholar 

  • Versteeg S, Mogk A, Schumann W. The Bacillus subtilis htpG gene is not involved in thermal stress management. Mol Gen Genomics. 1999;261(3):582–8.

    Article  CAS  Google Scholar 

  • Voellmy R. Transduction of the stress signal and mechanisms of transcriptional regulation of heat shock/stress protein gene expression in higher eukaryotes. Crit Rev Eukaryot Gene Expr. 1994;4(4):357–401.

    PubMed  CAS  Google Scholar 

  • Vos MJ, Hageman J, Carra S, Kampinga HH. Structural and functional diversities between members of the human HSPB, HSPH, HSPA, and DNAJ chaperone families. Biochemistry. 2008;47(27):7001–11.

    Article  PubMed  CAS  Google Scholar 

  • Wu C. Heat shock transcription factors: structure and regulation. Annu Rev Cell Dev Biol. 1995;11:441–69.

    Article  PubMed  CAS  Google Scholar 

  • Xu Q. Role of heat shock proteins in atherosclerosis. Arterioscler Thromb Vasc Biol. 2002;22:1547–59.

    Article  PubMed  CAS  Google Scholar 

  • Zylicz M, Wawrzynow A. Insights into the function of Hsp70 chaperones. IUBMB Life. 2001;51(5):283–7.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Betul Karademir .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Karademir, B., Sari-Kaplan, G. (2018). Heat Shock Protein (HSP). In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, Cham. https://doi.org/10.1007/978-3-319-67199-4_101809

Download citation

Publish with us

Policies and ethics