Encyclopedia of Signaling Molecules

2018 Edition
| Editors: Sangdun Choi

RCAN

  • Ignacio Guerrero-Ros
  • Rut Valdor
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-67199-4_101514

Synonyms

Historical Background

The protein family of the regulators of calcineurin (RCANs), previously termed as DSCR, MCIP, or calcipressins among other names, has been shown to function as regulators of the calcium-calmodulin regulated phosphatase calcineurin. The gene encoding for the first RCAN protein was cloned more than 20 years ago and named DSCR1, as it was identified in the Down syndrome critical region, which encoded a proline-rich protein highly...

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References

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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  1. 1.Department of PathologyAlbert Einstein College of MedicineBronxUSA
  2. 2.Department of Human Anatomy and PsychobiologyUniversity of Murcia School of Medicine and Instituto Murciano de Investigación BiosanitariaMurciaSpain