Pathology of the Pleura and Mediastinum

2018 Edition
| Editors: Timothy Craig Allen, Saul Suster

Liposarcoma, Primary Pleural

  • Christopher P. Marquez
  • Timothy Craig Allen
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-66796-6_2883

Synonyms

No terms are synonymous with primary pleural liposarcoma.

Definition

Liposarcoma (LPS) is one of the most common types of sarcomas seen in adults. It is believed that LPS are derived from the residual rests of primitive mesenchymal tissue; however, on rare occasions they may also develop from a pre-existing lipoma. They are commonly found as a primary tumor in the deep soft tissues of the proximal extremities, and retroperitoneum. Metastasis to the lung in not uncommon; however, primary LPS in the lung is rare, especially the pleura.

Clinical Features

  • Incidence

    Primary pleural LPS is exceedingly rare with less than 20 cases reported

  • Age

    Age of presentation ranges from 19 to 80 years of age, with a median age of 50 years.

  • Sex

    Older men are predominately affected; however, it may occur in women as well.

  • Site

    Pleura

  • Treatment

    Treatment consists of surgical resection, radiation, or chemotherapy. Radiation therapy seems to show some benefit.

  • Outcome

    Determination of prognosis has...

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References and Further Reading

  1. Cagle, P. T., et al. (2004). Color atlas and text of pulmonary pathology (1st ed.). Philadelphia: Lippincott Williams & Wilkins.Google Scholar
  2. Dagli, A. F., Pehlivan, S., & Ozercan, M. R. (2010). Pleural liposarcoma mimicking carcinoma in pleural effusion cytology: A case report. Acta Cytologica, 54, 601–604.CrossRefPubMedGoogle Scholar
  3. Elsayed, H., & Gosney, J. (2011). A massive pleural-based tumour: The challenge of diagnosis. Revista Portuguesa de Pneumologia, 17, 275–277.CrossRefPubMedGoogle Scholar
  4. Gattuso, P., et al. (2010). Differential diagnosis in surgical pathology (2nd ed.). Philadelphia: Saunders.Google Scholar
  5. Okby, N. T., & Travis, W. D. (2000). Liposarcoma of the pleural cavity: Clinical and pathologic features of 4 cases with a review of the literature. Archives of Pathology and Laboratory Medicine, 124, 699–703.PubMedGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of PathologyThe University of Texas Medical BranchGalvestonUSA