Rosen, who first described these lesions in 1986, gave the following definition: “mucin containing cysts lined by flat or low cubical epithelium with or without extravasated mucin” (Rosen 1986).
Since the first description by Rosen in 1986, single case reports or relatively small series have been published. With the introduction of screening programs, the incidence increased due to the associated microcalcifications. The incidence of MCLLs is very low, ranging from 0.25% (Jaffer et al. 2011) to <1% (102 MCLL cases in a population of 13,412 women with biopsy proven benign breast disease) (Meares et al. 2016).
Since MCLLs are very often associated with microcalcifications and are discovered mainly on screening mammograms, the mean age reported is 53–55 years.
No MCLLs have been described in male patients to date.
No specific site in the breast has been described.
The majority of these lesions are...
References and Further Reading
- Tan, P. H., Tse, G. M. K., & By, B. H. (2008). Mucinous breast lesions: Diagnostic challenges. Journal of Clinical Pathology, 6, 11–19.Google Scholar