Breast Pathology

2020 Edition
| Editors: Anna Sapino, Janina Kulka

Atypical Vascular Lesions

  • Lauren E. Rosen
  • Thomas KrauszEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-62539-3_4741

Synonyms

Cutaneous atypical vascular lesions (AVLs) of the breast have been described using a variety of terms including post-mastectomy lymphangiomatosis, benign lymphangiomatous papules, benign lymphangioendothelioma, acquired lymphangiectasis, and lymphangioma circumscriptum (Baker and Schnitt 2017; Weaver and Billings 2009).

Definition

AVLs are benign vascular proliferations of the skin that occur following radiation therapy for breast cancer within the field of radiation. The term AVL was proposed by Fineberg and Rosen in 1994 to reflect the fact that these lesions were occasionally mistaken for angiosarcoma, and because their relationship to post-irradiation angiosarcomas (PIAS) is not fully understood (Fineberg and Rosen 1994).

Clinical Features

  • Incidence

    AVLs occur in the field of radiation after radiation therapy for breast cancer, with a latency period of 1 month to 20 years, occurring most frequently between 3 and 6 years post-treatment (Ginter et al. 2017).

  • Age

    AVLs are...

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References

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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of PathologyUniversity of ChicagoChicagoUSA