Breast Pathology

2020 Edition
| Editors: Anna Sapino, Janina Kulka

Adenosis, Other Types

  • Manuela LacerdaEmail author
  • Paulo Figueiredo
Reference work entry


Adenomyoepithelial adenosis/apocrine adenosis/secretory adenosis; Adenosis tumor/nodular adenosis; Simple adenosis/adenosis; Tubular adenosis


Adenomyoepithelial adenosis: A benign proliferative lesion characterized by the simultaneous hyperplasia in both glandular and myoepithelial cells of the units of the lobules.

Adenosis tumor: A clinically and/or macroscopically recognizable breast lesion that, histologically, primarily consists of sclerosing adenosis ( Sclerosing Adenosis).

Tubular adenosis: A very rare benign lesion composed of disorderly growing, noncrowded narrow tubules that may mimic invasive carcinoma.

Simple adenosis: An increase in size and number of lobules.

Clinical Features

  • Incidence

    Adenomyoepithelial adenosis: In the literature, few cases are reported.

    Adenosis tumor: Rare.

    Tubular adenosis: Very rare, only few cases have been reported.

    Simple adenosis: Incidental finding in surgical specimens.

  • Age

    Adenomyoepithelial adenosis: The age range is...

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References and Further Reading

  1. Bonser, G. M., Dossett, J. A., & Jull, J. W. (1961). Human and experimental breast cancer. London: Pitman Medical Publications Co. Ltd.Google Scholar
  2. Da Silva, L., Buck, L., Simpson, P. T., Reid, L., McCallum, N., Madigan, B. J., & Lakhani, S. R. (2009). Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis. Virchows Archive, 454, 107–114.CrossRefGoogle Scholar
  3. DiPiro, P., Gulizia, J. A., Lester, S. C., & Meyer, J. E. (2000). American Journal of Radiology, 175, 31–34.Google Scholar
  4. Erel, S., Tuncbilek, I., Kismet, K., Kilicoglu, B., Ozer, E., & Mehmet, A. A. (2008). Adenomyoepithelial adenosis of the breast: Clinical, radiological and pathological findings for differential diagnosis. Breast Cancer, 3, 427–430.Google Scholar
  5. European guidelines for quality assurance in breast cancer screening and diagnosis. (2006). European Commission, 4th edn 6a (pp. 221–256).Google Scholar
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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Instituto de Patologia e Imunologia Molecular da Universidadedo Porto (IPATIMUP)PortoPortugal
  2. 2.Instituto Português de Oncologia de CoimbraCoimbraPortugal