Cognitive Affective Syndrome
Cerebellar cognitive affective syndrome
First described by Schmahmann and Sherman (1998), cerebellar cognitive affective syndrome (CAS) refers to a cluster of impairments involving higher-order cognitive processes and affective functioning. Symptoms tend to cluster in executive dysfunction, including problems with planning, set shifting, verbal fluency, abstract reasoning, perseveration, attentional dysregulation, hyperactivity, impulsivity and disinhibition, and deficits in working memory. However, symptoms may also include visuospatial disorders, expressive language disorders, affective abnormalities, difficulties with visuospatial organization, visual memory, logical sequencing, and blunted or inappropriate affect (Schmahmann and Sherman 1998).
Causes and Correlates of CAS
The co-occurrence of these cognitive and affective symptoms arises from the disruption of neuroanatomical circuits connecting the cerebellum with frontal, parietal, temporal,...