Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Cognitive Affective Syndrome

  • Robert RiderEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_99


Cerebellar cognitive affective syndrome


First described by Schmahmann and Sherman (1998), cerebellar cognitive affective syndrome (CAS) refers to a cluster of impairments involving higher-order cognitive processes and affective functioning. Symptoms tend to cluster in executive dysfunction, including problems with planning, set shifting, verbal fluency, abstract reasoning, perseveration, attentional dysregulation, hyperactivity, impulsivity and disinhibition, and deficits in working memory. However, symptoms may also include visuospatial disorders, expressive language disorders, affective abnormalities, difficulties with visuospatial organization, visual memory, logical sequencing, and blunted or inappropriate affect (Schmahmann and Sherman 1998).

Current Knowledge

Causes and Correlates of CAS

The co-occurrence of these cognitive and affective symptoms arises from the disruption of neuroanatomical circuits connecting the cerebellum with frontal, parietal, temporal,...

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References and Readings

  1. Schmahmann, J., & Sherman, J. (1998). The cerebellar cognitive affective syndrome. Brain, 121, 561–579.PubMedCrossRefPubMedCentralGoogle Scholar
  2. Schmahmann, J., Weilburg, J. D., Sherman, J. B., & Janet, C. (2007). The neuropsychiatry of the cerebellum – Insights from the clinic. Cerebellum, 6(3), 254–267.PubMedCrossRefPubMedCentralGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of PsychologyDrexel UniversityPhiladelphiaUSA