Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Brain Tumor

  • Ethan MoitraEmail author
  • Daniel Smith
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_94


An abnormal mass of tissue in which some cells (glial or non-glial) grow and multiply uncontrollably. A tumor can be benign or malignant. It is associated with damage or mutation to the TP53 gene on human chromosome 17. P53 regulates the cell cycle and functions in tumor suppression. A tumor can cause damage by increasing pressure in the brain, by shifting the brain or pushing against the skull, and by invading and damaging nerves and healthy brain tissue. Some tumors may be truly indolent in their growth, growing so slowly that they are present for an unknown length of time because symptoms are less gross and disruptive. Those that are actively growing may be more likely to present with the following symptoms, depending on tumor locus: headaches; nausea or vomiting; seizures or convulsions; difficulty in thinking, speaking, or finding words; personality changes; weakness or paralysis in one part or one side of the body; loss of balance; vision changes; confusion and...

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References and Readings

  1. Levin, V. A., Leibel, S. A., & Gutin, P. H. (2001). Neoplasms of the central nervous system. In V. T. DeVita, S. Hellman, & S. A. Rosenberg (Eds.), Cancer: Principles and practice of oncology (pp. 2100–2160). Philadelphia: Lippincott, Williams, & Wilkins.Google Scholar
  2. Price, T. R. P., Goetz, K. L., & Lovell, M. R. (2007). Neuropsychiatric aspects of brain tumors. In S. C. Yudofsky & R. E. Hales (Eds.), The American Psychiatric Publishing textbook of neuropsychiatry and behavioral neurosciences (5th ed., pp. 735–764). Washington, DC: American Psychiatric Association.Google Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Psychiatry and Human BehaviorBrown UniversityProvidenceUSA
  2. 2.Department of PsychologyDrexel UniversityPhiladelphiaUSA