Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan


  • Efrain Antonio GonzalezEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_9274

Generic Name


Brand Name

Pristiq, Khedzla


Antidepressants, serotonin norepinephrine reuptake inhibitors.

Proposed Mechanism(s) of Action

Increases serotonin and norepinephrine by blocking both serotonin and norepinephrine reuptake pumps.


Major depressive disorder.

Off-Label Use

Neuropathic pain, chronic pain, generalized anxiety disorder, stress urinary incontinence, and fibromyalgia.

Side Effects


Seizures, hypomania, and suicidal ideation.


Nausea, headache, diarrhea, dry mouth, constipation, fatigue.

References and Readings

  1. Physicians’ desk reference (71st ed.) (2017). Montvale: Thomson PDR.Google Scholar
  2. Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.Google Scholar

Additional Information

  1. Free Drug Online and PDA Software. www.medscapepsychiatry.com
  2. Free Drug Online and PDA Software. www.epocrates.com

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.College of Psychology, Nova Southeastern UniversityFort LauderdaleUSA
  2. 2.Utah State UniversityLoganUSA