Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Ventricle-to-Brain (VBR) Ratio

  • David F. TateEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_9075


3-D neuroimaging; Brain atrophy measurement; Computed tomography; CT; Magnetic resonance imaging; MRI; Planimetric mapping; VBR; Ventricle measurement; Ventricle-to-brain ratio; Volumetric measurement


Ventricle-to-brain ratio (VBR) refers to a brain volumetric measurement calculated as a ratio of ventricle volume (i.e., lateral, III, and IV ventricles total) to brain parenchymal volume (white and gray matter total). It originated in the era of pneumoencephalography (a now superseded radiographic technique, Haug 1962, 1982) when planimetric methods (i.e., the study of planes, angles, distances, and areas) were used to calculate this ratio from a single slice (Haug 1962, 1982). However, in the era of three-dimensional (3-D) computed tomography (CT) and magnetic resonance imaging (MRI), this measure now incorporates the volumetric information available in cubic centimeters (cm 3 or cc’s) (Blatter et al. 1997; Gale et al. 1995) and is calculated using the following...
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References and Readings

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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Brain Imaging and Behavior Laboratory, Missouri Institute of Mental Health (MIMH)University of Missouri, St. Louis (UMSL)BerkeleyUSA