Skip to main content

Regional Cerebral Blood Flow

  • Reference work entry
  • First Online:
  • 6 Accesses

Definition

Regional cerebral blood flow is defined as the amount of blow flow to a specific region of the brain in a given time period.

Current Knowledge

Cerebral blood flow is tightly regulated to meet the metabolic demands of the brain. Meticulous regulation of blood flow is imperative because brain tissue can be damaged with either too much blood flow, resulting in increased intracranial pressure, or too little blood flow, resulting in ischemia. Cerebral blood flow is regulated by cerebral perfusion pressure and cerebral vascular resistance. The control of cerebral blood flow is determined by You have any other part on Howard Kaplan do you four major mechanisms: metabolic control, neural control, chemical control, and pressure autoregulation. Metabolic regulation is the coupling of regional cerebral metabolic demand for oxygen and glucose generated by local neural activity and blood flow through that tissue. Intrinsic mechanisms in the brain regulate cerebral blood flow and permits...

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   899.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD   1,099.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References and Readings

  • Dotson, V. M., Beason-Held, L., Kraut, M. A., & Resnick, S. M. (2009). Longitudinal study of chronic depressive symptoms and regional cerebral blood flow in older men and women. International Journal of Geriatric Psychiatry, 24(8), 809–819.

    Article  PubMed  PubMed Central  Google Scholar 

  • Jagust, W. J. (2006). Clinical studies of cerebral blood flow in Alzheimer’s disease. Annals of the New York Academy of Sciences, 826, 254–262.

    Article  Google Scholar 

  • Jennings, J. R., Muldoon, M. F., Ryan, C., Gach, H. M., Heim, A., Sheu, L. K., & Gianaros, P. J. (2017). Prehypertensive blood pressures and regional cerebral blood flow independently relate to cognitive performance in midlife. Journal of the American Heart Association, 6(3).

    Google Scholar 

  • ter Laan, M., van Dijk, J. M. C., Elting, J. W. J., et al. (2013). Sympathetic regulation of cerebral blood flow in humans: A review. British Journal of Anaesthesia, 111(3), 361–367.

    Article  PubMed  Google Scholar 

  • Meier, T. B., Bellgowan, P. S., Singh, R., Kuplicki, R., Polanski, D. W., & Mayer, A. R. (2015). Recovery of cerebral blood flow following sports-related concussion. JAMA Neurology, 72(5), 530–538.

    Article  PubMed  Google Scholar 

  • Salehi, A., Zhang, J. H., & Obenaus, A. (2017). Response of the cerebral vasculature following traumatic brain injury. Journal of Cerebral Blood Flow Metabolism. Epub ahead of print.

    Google Scholar 

  • Van Larr, P. J., van der Graaf, Y., Mali, W. P., van der Grond, J., & Hendrikse, J. (2008). Effect of cerebrovascular risk factors on regional cerebral blood flow. Radiology, 246, 198–204.

    Article  Google Scholar 

  • Zubieta, J. K., Heitzeg, M. M., Xu, Y., Koeppe, R. A., Ni, L., Guthrie, S., et al. (2005). Regional cerebral blood flow responses to smoking in tobacco smokers after overnight abstinence. The American Journal of Psychiatry, 162, 567–577.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Anuj Sharma .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG, part of Springer Nature

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Sharma, A., Zasler, N.D. (2018). Regional Cerebral Blood Flow. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_68

Download citation

Publish with us

Policies and ethics