Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Regional Cerebral Blood Flow

  • Anuj SharmaEmail author
  • Nathan D. Zasler
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_68


Regional cerebral blood flow is defined as the amount of blow flow to a specific region of the brain in a given time period.

Current Knowledge

Cerebral blood flow is tightly regulated to meet the metabolic demands of the brain. Meticulous regulation of blood flow is imperative because brain tissue can be damaged with either too much blood flow, resulting in increased intracranial pressure, or too little blood flow, resulting in ischemia. Cerebral blood flow is regulated by cerebral perfusion pressure and cerebral vascular resistance. The control of cerebral blood flow is determined by You have any other part on Howard Kaplan do you four major mechanisms: metabolic control, neural control, chemical control, and pressure autoregulation. Metabolic regulation is the coupling of regional cerebral metabolic demand for oxygen and glucose generated by local neural activity and blood flow through that tissue. Intrinsic mechanisms in the brain regulate cerebral blood flow and permits...

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References and Readings

  1. Dotson, V. M., Beason-Held, L., Kraut, M. A., & Resnick, S. M. (2009). Longitudinal study of chronic depressive symptoms and regional cerebral blood flow in older men and women. International Journal of Geriatric Psychiatry, 24(8), 809–819.PubMedPubMedCentralCrossRefGoogle Scholar
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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Virginia Commonwealth University School of MedicineRichmondUSA
  2. 2.Concussion Care Centre of Virginia, Ltd.RichmondUSA