Goldman-Rakic, Patricia (1937–2003)
Landmark Clinical, Scientific, and Professional Contributions
Originally trained as a psychologist, Patricia Goldman-Rakic is universally recognized as one of the most prolific and creative neuroscientists of her generation, having authored or coauthored over 300 publications and coauthored three books on topics ranging from the ability of the brain to compensate for early injury to the development of a seminal model of working memory function that continues to stimulate leading-edge research in cognitive neuroscience and neuropsychology. She was a pioneer in cross-platform methodology – the use of multilevel techniques to fully elucidate neural processes and mechanisms. Her research program utilized both structural and neurochemical lesion methods, electrophysiology, immunocytochemistry, receptor autoradiography, and sophisticated behavioral methods.
Early in her career, Goldman-Rakic’s work on the cognitive effects of pre- and postnatal cortical lesions in infant rhesus monkeys (Maca...
References and Readings
- Goldman-Rakic, P. S., Lidow, M. S., Smiley, J. F., & Williams, M. S. (1992). The anatomy of dopamine in monkey and human prefrontal cortex. Journal of Neural Transmission (Supplement), 36, 163–177.Google Scholar
- In Memoriam: Patricia Goldman-Rakic, Preeminent Yale Neuroscientist who Made Groundbreaking Discoveries in Working Memory and Explored the Brain’s Frontal Lobe. Yale News. August 1, 2003.Google Scholar