Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Goldman-Rakic, Patricia (1937–2003)

  • Russell M. BauerEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_619

Landmark Clinical, Scientific, and Professional Contributions

  • Originally trained as a psychologist, Patricia Goldman-Rakic is universally recognized as one of the most prolific and creative neuroscientists of her generation, having authored or coauthored over 300 publications and coauthored three books on topics ranging from the ability of the brain to compensate for early injury to the development of a seminal model of working memory function that continues to stimulate leading-edge research in cognitive neuroscience and neuropsychology. She was a pioneer in cross-platform methodology – the use of multilevel techniques to fully elucidate neural processes and mechanisms. Her research program utilized both structural and neurochemical lesion methods, electrophysiology, immunocytochemistry, receptor autoradiography, and sophisticated behavioral methods.

  • Early in her career, Goldman-Rakic’s work on the cognitive effects of pre- and postnatal cortical lesions in infant rhesus monkeys (Maca...

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References and Readings

  1. Amy F.T Arnsten, (2003) Patricia Goldman–Rakic. Neuron 40(3):465–470CrossRefGoogle Scholar
  2. Goldman-Rakic, P. S. (1980). Morphological consequences of prenatal injury to the primate brain. Progress in Brain Research, 53, 1–19.PubMedPubMedCentralGoogle Scholar
  3. Goldman-Rakic, P. S. (1988). Topography of cognition: Parallel distributed networks in primate association cortex. Annual Review of Neuroscience, 11, 137–156.PubMedCrossRefPubMedCentralGoogle Scholar
  4. Goldman-Rakic, P. S. (1990). Cellular and circuit basis of working memory in prefrontal cortex of nonhuman primates. Progress in Brain Research, 85, 325–335.PubMedCrossRefPubMedCentralGoogle Scholar
  5. Goldman-Rakic, P. S. (1994). Working memory dysfunction in schizophrenia. Journal of Neuropsychiatry and Clinical Neuroscience, 6, 348–357.CrossRefGoogle Scholar
  6. Goldman-Rakic, P. S. (1995). Cellular basis of working memory. Neuron, 14, 477–485.PubMedCrossRefPubMedCentralGoogle Scholar
  7. Goldman-Rakic, P. S. (1996a). Memory: Recording experience in cells and circuits: diversity in memory research. Proceedings of the National Academy of Sciences USA, 93, 13435–13437.CrossRefGoogle Scholar
  8. Goldman-Rakic, P. S. (1996b). Regional and cellular fractionation of working memory. Proceedings of the National Academy of Sciences USA, 93, 13473–13480.CrossRefGoogle Scholar
  9. Goldman-Rakic, P. S. (1998). The cortical dopamine system: Role in memory and cognition. Advances in Pharmacology, 42, 707–711.PubMedCrossRefPubMedCentralGoogle Scholar
  10. Goldman-Rakic, P. S. (1999). The physiological approach: Functional architecture of working memory and disordered cognition in schizophrenia. Biological Psychiatry, 46, 650–651.PubMedCrossRefPubMedCentralGoogle Scholar
  11. Goldman-Rakic, P. S., & Selemon, L. D. (1990). New frontiers in basal ganglia research. Introduction. Trends in Neuroscience, 13, 241–244.CrossRefGoogle Scholar
  12. Goldman-Rakic, P. S., & Selemon, L. D. (1997). Functional and anatomical aspects of prefrontal pathology in schizophrenia. Schizophrenia Bulletin, 23, 437–458. (50th most cited paper in history of Schizophrenia Bulletin).PubMedCrossRefPubMedCentralGoogle Scholar
  13. Goldman-Rakic, P. S., Lidow, M. S., Smiley, J. F., & Williams, M. S. (1992). The anatomy of dopamine in monkey and human prefrontal cortex. Journal of Neural Transmission (Supplement), 36, 163–177.Google Scholar
  14. In Memoriam: Patricia Goldman-Rakic, Preeminent Yale Neuroscientist who Made Groundbreaking Discoveries in Working Memory and Explored the Brain’s Frontal Lobe. Yale News. August 1, 2003.Google Scholar
  15. Levy, R., & Goldman-Rakic, P. S. (1999). Association of storage and processing functions in the dorsolateral prefrontal cortex of the nonhuman primate. Journal of Neuroscience, 19, 5149–5158.PubMedCrossRefPubMedCentralGoogle Scholar
  16. Levy, R., & Goldman-Rakic, P. S. (2000). Segregation of working memory functions within the dorsolateral prefrontal cortex. Experimental Brain Research, 133, 23–32.PubMedCrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Clinical and Health PsychologyUniversity of FloridaGainesvilleUSA