Type 1 diabetes, previously termed juvenile-onset or insulin-dependent diabetes; Type 2 diabetes, previously termed non-insulin-dependent diabetes or adult-onset diabetes
Short Description or Definition
Diabetes mellitus is a complex set of metabolic disorders involving chronically high levels of blood glucose (hyperglycemia) secondary to the impaired production of the hormone, insulin. Classic symptoms include polyuria (excessive urine), polydipsia (intense thirst), polyphagia (intense hunger), and fatigue.
There are two main types of diabetes: type 1 diabetes is much less common, accounting for about 10% of all diagnosed cases, and is characterized by an inability to secrete insulin due to the destruction of the beta cells of the pancreas. This type of diabetes usually is diagnosed before the age 20. The more common type 2 typically occurs in adulthood and results from the development of insulin resistance, which can result in chronic hyperglycemia. Risk...
References and Readings
- Brands, A. M. A., van den Berg, E., Manschot, S. M., Biessels, G. J., Kappelle, L. J., de Haan, E. H. F., & Kessels, R. P. C. (2007). A detailed profile of cognitive dysfunction and its relation to psychological distress in patients with type 2 diabetes mellitus. Journal of the International Neuropsychological Society, 13, 288–297.PubMedCrossRefPubMedCentralGoogle Scholar
- Jacobson, A. M., Musen, G., Ryan, C. M., Silvers, N., Cleary, P., Waberski, B., Burwod, A., Weinger, K., Bayless, M., Dahms, W., Harth, J., & The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study Research Group. (2007). Long-term effect of diabetes and its treatment on cognitive function. The New England Journal of Medicine, 356, 1842–1852.PubMedCrossRefPubMedCentralGoogle Scholar