Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Relapsing-Remitting Multiple Sclerosis

  • Kathleen L. FuchsEmail author
  • John DeLuca
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_518

Synonyms

Exacerbating-remitting multiple sclerosis

Short Description or Definition

Relapsing-remitting multiple sclerosis (RRMS) describes the initial course of approximately 85% of patients diagnosed with MS. There are discrete episodes (aka “relapses,” “attacks,” “flare-ups,” or “exacerbations”) of neurologic dysfunction lasting at least 24 h followed by full or partial recovery and a period in which there is no symptom progression or accumulation of disability (aka “remission”; see Fig. 1). Across individuals with RRMS, there is a great deal of variability in the time between relapses and in the severity of relapse symptoms. Recovery from relapses may be incomplete, and thus a certain amount of residual neurologic dysfunction may persist (see Fig. 2). When symptoms progress outside relapse periods, the person is considered to have entered the secondary progressive stage of the disease.
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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of NeurologyUniversity of Virginia Health SystemCharlottesvilleUSA
  2. 2.Research DepartmentKessler FoundationWest OrangeUSA