Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Midbrain Raphe

  • George LeichnetzEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_337


The midbrain raphe is on the “midline seam” or raphe of the caudal midbrain and contains the cell bodies of serotonergic neurons that primarily give rise to ascending serotonergic projections to higher levels of the brain that are involved in sleep mechanisms. Typically, the term includes the dorsal raphe nucleus and superior central raphe nucleus. Lesions of the midbrain raphe typically result in an inability to go into slow-wave synchronized sleep.


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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Virginia Commonwealth UniversityRichmondUSA