Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Corpus Callosum

  • Jeff DupreeEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_308

Synonyms

Commissural magna; Corporis callosi; Interhemispheric commissure

Definition

Corpus callosum is the largest axonal tract of the adult brain that provides symmetrical connections between the two hemispheres.

Current Knowledge

The corpus callosum is the largest commissure of the adult brain that provides a bridge for the passing of information from one cerebral hemisphere to the other by 200–300 million myelinated and unmyelinated axons. The size of the corpus callosum varies greatly but is generally larger in females than in males. In the human, the corpus callosum begins development around the 11th week of gestation and continues through adolescence. Initially, the corpus callosum is composed of astrocytic processes, which serve as conduits for growing axons extending to the contralateral hemisphere. This interhemispheric commissure lies beneath the cortex at the bottom of the cerebral longitudinal fissure. It forms much of the roof of the lateral ventricles and is composed of...

This is a preview of subscription content, log in to check access.

References and Readings

  1. Barr, M., & Kiernan, J. (1983). The human nervous system – An anatomical viewpoint (4th ed.). Philadelphia: Harper and Row.Google Scholar
  2. Gazzaniga, M. S. (2005). Forty-five years of split-brain research and still going strong. Nature Reviews Neuroscience, 6(8), 653–659.CrossRefGoogle Scholar
  3. Haines, D. (2006). Fundamental neuroscience for basic and clinical applications (3rd ed.). Philadelphia: Churchill Livingstone Elsevier.Google Scholar
  4. Kandel, E., Schwartz, J. H., & Jessel, T. M. Principles of neural science (4th ed.). New York: McGraw-Hill.Google Scholar
  5. Paul, L. K., Brown, W. S., Adolphs, R., Tyszka, J. M., Richards, L. J., Mukherjee, P., et al. (2007). Agenesis of the corpus callosum: Genetic, developmental and functional aspects of connectivity. Nature Reviews Neuroscience, 8(4), 287–299.PubMedCrossRefPubMedCentralGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Anatomy and NeurobiologyVirginia Commonwealth UniversityRichmondUSA