Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Cerebral Edema

  • Gary TyeEmail author
  • John Brown
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_305


Cytotoxic edema; Vasogenic edema


Cerebral edema is an increase in the water content of the brain that leads to brain swelling. It may be divided into two broad categories: vasogenic and cytotoxic.

Vasogenic edema involves a disruption in the blood-brain barrier with leakage of fluid from the intravascular space.

In cytotoxic edema, the blood-brain barrier is intact, and there is an increase in the intracellular fluid compartment.


References and Readings

  1. Beaumont, A., Marmarou, A., & Ward, J. D. (2001). Intracranial hypertension mechanisms and management. In D. G. McClone (Ed.), Pediatric neurosurgery (pp. 619–633). Philadelphia: W. B. Saunders.Google Scholar
  2. Greenberg, M. S. (1997). Handbook of neurosurgery. Lakeland: Greenberg Graphics.Google Scholar
  3. Rosenblum, W. I. (2007). Cytotoxic edema: Monitoring its magnitude and contribution to brain swelling. Journal of Neuropathology and Experimental Neurology, 66(9), 771–778.PubMedCrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.NeurosurgeryVirginia Commonwealth UniversityRichmondUSA
  2. 2.Medical College of GeorgiaAugustaUSA