Diffuse Axonal Injury
One of the major types of traumatic brain injury that results from acceleration-deceleration effects rather than direct impact on the brain. Typically, the injury is the result of high-speed situations such as motor vehicle accidents or violent shaking of the head from side to side. The forceful motion of injury disturbs the delicate underlying white matter tracts of the brain that are responsible for connecting the functional areas controlling motor skills, cognitive skills, language skills, and behavior. Because each neural cell or vessel has a fixed length and is held in position along its path by other cells, there is limited elasticity in any cell or vessel. Thus, acceleration-deceleration forces can disrupt cells and vessels despite an absence of direct trauma to the cell or vessel. Damage may result from stretching, twisting, or rotation. Diffuse axonal injury (DAI) is more likely to occur with lateral movements of the brain and least likely to occur with...
References and Readings
- Ubukata, S., Ueda, K., Sugihara, G., Yassin, W., Aso, T., Fukuyama, H., & Murai, T. (2016). Corpus callosum pathology as a potential surrogate marker of cognitive impairment in diffuse axonal injury. Journal of Neuropsychiatry and Clinical Neuroscience, 28, 97–103.PubMedCrossRefPubMedCentralGoogle Scholar