Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

L’etat Lacunaire

  • Elliot J. RothEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_2220


Lacunar state


In L’etat lacunaire, or lacunar state, the brain contains multiple small infarcts or lacunes, usually in the deep structures, especially the basal ganglia.

Current Knowledge

Similar to lacunar strokes, the lacunar state is associated with hypertension and atherosclerosis, the latter being present especially in the small deep vessels in the brain. Many small infarcts can result in dementia, characterized by loss of recent memory, alterations in orientation to time and space, and occasionally paranoia. Lacunar state is a common cause of vascular dementia. There also can be headache, vertigo, and light-headedness. Sensory loss and motor deficits such as ataxia, hemiparesis, and dysarthria, may occur, presenting similarly to lacunar stroke syndromes. Although the diagnosis can be made on clinical grounds, CT scanning and magnetic resonance imaging usually clearly demonstrate the multiple small cerebral infarctions.


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References and Readings

  1. Debette, S., Bombois, S., Bruandet, A., Delbeuck, X., Lepoittevin, S., Delmaire, C., et al. (2007). Subcortical hyperintensities are associated with cognitive decline in patients with mild cognitive impairment. Stroke, 38, 2924–2930.PubMedCrossRefGoogle Scholar
  2. Erkinjuntti, T. (2002). Subcortical vascular dementia. Cerebrovascular Diseases, 13, 58–60.PubMedCrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Physical Medicine and Rehabilitation, Northwestern University, Feinberg School of MedicineChicagoUSA