Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Appalic Syndrome

  • Dona LockeEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_221

Synonyms

Persistent vegetative state; Unresponsiveness wakefulness syndrome

Definition

Apallic syndrome is an older term that was first replaced by persistent vegetative state. More recently, unresponsive wakefulness syndrome (UWS) is the proposed nomenclature. The syndrome is a clinical condition describing patients who fail to show voluntary motor responsiveness in the presence of eyes-open wakefulness. Patients show reflexive behavior such as spontaneous breathing, but no signs of awareness of the self or the environment. A thorough clinical evaluation may be required to distinguish between UWS and other conditions, including coma, brain death, and locked-in syndrome.

Cross-References

References and Readings

  1. (1994). Medical aspects of the persistent vegetative state-first of two parts. NEJM, 330, 1499–1508.Google Scholar
  2. Multi-society task force on PVS (1994). Medical aspects of the persistent vegetative state-second of two parts. NEJM, 330, 1572–1579.Google Scholar
  3. Laureys, S., Celesia, G. G., Cohadon, F., Lavrijsen, J., et al. (2010). Unresponsive wakefulness syndrome: A new name for the vegetative state or apallic syndrome. BMC Medicine, 8, 68.Google Scholar
  4. van Erp, W., Lavrijsen, J. C. M., van de Laar, F. A, Vos, P . E., Laureys S., Koopmans, R. T. C. M. (2014). The vegetative state/unresponsiveness wakefulness syndrome: A systematic review of prevalence studies. European Journal of Neurology, 21, 1361–1368.PubMedCrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Psychiatry and PsychologyMayo ClinicScottsdaleUSA