Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Coronary Disease

  • Elliot J. RothEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_2172

Synonyms

Atherosclerotic heart disease; Coronary artery disease; Coronary heart disease; Ischemic heart disease

Definition

Coronary disease, or coronary artery disease (CAD), results from atherosclerosis, or narrowing of the arteries that provide blood supply to the heart muscle (“myocardium”).

Current Knowledge

Atherosclerosis, which is the process by which cholesterol and fat deposits adhere to the inside walls of blood vessels, creates “plaques” that block the blood supply through blood vessels. When this narrowing or occlusive process blocks the coronary artery, the accompanying obstruction to blood flow reduces the supply of oxygen and nutrients to the heart muscle, creating ischemia that causes chest pain (“angina pectoris”), or death of the cells of the heart (“myocardial infarction”). At times, it can cause other problems such as arrhythmias (abnormal heart rhythm) or congestive heart failure, in which the heart is unable to pump sufficient blood to the remainder of the body....

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References and Readings

  1. Hansson, G. K. (2005). Inflammation, atherosclerosis, and coronary artery disease. New England Journal of Medicine, 352, 1685–1695.PubMedCrossRefPubMedCentralGoogle Scholar
  2. Virmani, R., Kolodgie, F. D., Burke, A. P., Farb, A., & Schwartz, S. T. (2000). Lessons from sudden coronary death: A comprehensive morphological classification scheme for atherosclerotic lesions. Arteriosclerosis, Thrombosis, and Vascular Biology, 20, 1262–1275.PubMedCrossRefPubMedCentralGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Physical Medicine and RehabilitationNorthwestern University, Feinberg School of MedicineChicagoUSA