Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Major Depression

  • Robert G. FrankEmail author
  • Zoë N. Swaine
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_2129


Clinical depression; Major depressive disorder; Unipolar depression

Short Definition

Major depression is a mood disorder that presents with at least one major depressive episode that lasts more than 2 weeks. People with major depression typically experience persistent depressed/sad mood or anhedonia and usually experience several of the following symptoms: feelings of worthlessness or guilt, problems with concentration, suicidal thoughts, changes in weight or appetite, hypersomnia or insomnia, fatigue, and psychomotor retardation or agitation. These symptoms occur most of the days and significantly interfere with the individuals functioning or cause them significant distress. In children or adolescents, irritability may be the primary criteria, instead of depressed mood.


Major depression is a mood disorder, and is categorized as major depressive disorder, single episode or major depressive disorder, recurrent. Major depressive disorder, single episode consists...

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.University of New MexicoAlbuquerqueUSA
  2. 2.Keele UniversityKeeleUK