Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Irritable Bowel Syndrome

  • Natalie DattiloEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_2079

Short Description or Definition

Irritable bowel syndrome (IBS) is characterized by chronic abdominal pain or discomfort and altered bowel habits. In the absence of detectable organic causes, IBS is referred to as a functional disorder, which is defined by symptom-based criteria known as the “Rome criteria” (Longstreth et al. 2006).

Categorization

Symptom onset must occur at least 6 months before diagnosis.

On the basis of predominant bowel habit, IBS is categorized into three subgroups:
  1. 1.

    IBS with diarrhea

     
  2. 2.

    IBS with constipation

     
  3. 3.

    IBS with mixed bowel habits

     

Epidemiology

IBS is one of the most common syndromes seen by gastroenterologists and primary care providers, with a prevalence rate of 10–15% in industrialized countries (Drossman et al. 2002). Despite its relatively high prevalence rate, only about 10–30% of afflicted individuals seek medical care (Pae et al. 2007). Women are affected about twice as often as men in most population-based samples (Whitehead et al. 2002),...

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References and Readings

  1. Berman, S. M., Naliboff, B. D., Suyenobu, B., Labus, J. S., Stains, J., Ohning, G., et al. (2008). Reduced brainstem inhibition during anticipated pelvic visceral pain correlates with enhanced brain response to the visceral stimulus in women with irritable bowel syndrome. The Journal of Neuroscience, 28, 349–359.PubMedCrossRefGoogle Scholar
  2. Bradesi, S., Tillisch, K., & Mayer, E. (2006). Emerging drugs for irritable bowel syndrome. Expert Opinion on Emerging Drugs, 11, 293–313.PubMedCrossRefGoogle Scholar
  3. Brandt, L. J., Bjorkman, D., Fennerty, M. B., Lock, G. R., Olden, K., Peterson, W., et al. (2002). Systematic review on the management of irritable bowel syndrome. American Journal of Gastroenterology, 97, S7–S26.PubMedGoogle Scholar
  4. Drossman, D. A., Camilleri, M., Mayer, E. A., & Whitehead, W. E. (2002). AGA technical review on irritable bowel syndrome. Gastroenterology, 123, 2108–2131.PubMedCrossRefPubMedCentralGoogle Scholar
  5. Guthrie, E., Creed, F., Fernandes, L., Ratcliffe, J., Van der Jagt, J., Martin, J., et al. (2003). Cluster analysis of symptoms and health seeking behaviour differentiates subgroups of patients with severe irritable bowel syndrome. Gut, 52, 1616–1622.PubMedPubMedCentralCrossRefGoogle Scholar
  6. Hayee, B., & Forgacs, I. (2007). Psychological approach to managing irritable bowel syndrome. British Medical Journal, 334, 1105–1109.PubMedCrossRefGoogle Scholar
  7. Kim, D. Y., & Camilleri, M. (2000). Serotonin: A mediator of the brain-gut connection. American Journal of Gastroenterology, 95, 2698–2709.PubMedPubMedCentralGoogle Scholar
  8. Lackner, J. M., Mesmer, C., Morley, S., Dowzer, C., & Hamilton, S. (2004). Psychological treatments for irritable bowel syndrome: A systematic review and meta-analysis. Journal of Consulting and Clinical Psychology, 72, 1100–1113.PubMedCrossRefGoogle Scholar
  9. Levy, R. L., Von Korff, M., Whitehead, W. E., Stang, P., Saunders, K., Jhingran, P., et al. (2001). Costs of care for irritable bowel syndrome patients in a health maintenance organization. American Journal of Gastroenterology, 96, 3122–3129.PubMedCrossRefGoogle Scholar
  10. Longstreth, G. F., Thompson, W. G., Chey, W. D., Houghton, L. A., Mearin, F., & Spiller, R. C. (2006). Functional bowel disorders. In D. A. Drossman, E. Corazziari, M. Delvauz, et al. (Eds.), Rome III: The functional gastrointestinal disorders (3rd ed.). McLean: Degnon.Google Scholar
  11. Maxion-Bergemann, S., Thielecke, F., Abel, F., & Bergemann, R. (2006). Costs of irritable bowel syndrome in the UK and US. PharmacoEconomics, 24, 21–37.PubMedCrossRefGoogle Scholar
  12. Mayer, E. A. (2008). Irritable bowel syndrome. The New England Journal of Medicine, 358, 1692–1699.PubMedCrossRefGoogle Scholar
  13. Mertz, H. R. (2003). Irritable bowel syndrome. New England Journal of Medicine, 349, 2136–2146.PubMedCrossRefGoogle Scholar
  14. Mertz, H. R., Morgan, V., Tanner, G., Pickens, D., Price, R., Shyr, Y., et al. (2000). Regional cerebral activation in irritable bowel syndrome and control subjects with painful and nonpainful rectal distention. Gastroenterology, 118, 842–848.PubMedCrossRefGoogle Scholar
  15. Orr, W. C., Crowell, M. D., Lin, B., Harnish, M. J., & Chen, J. D. (1997). Sleep and gastric function in irritable bowel syndrome: Derailing the brain-gut axis. Gut, 41, 390–393.PubMedPubMedCentralCrossRefGoogle Scholar
  16. Pae, C. U., Masand, P. S., Ajwani, N., Lee, C., & Patkar, A. A. (2007). Irritable bowel syndrome in psychiatric perspective: A comprehensive review. International Journal of Clinical Practice, 61, 1708–1718.PubMedCrossRefGoogle Scholar
  17. Read, N. W., & Gwee, K. A. (1994). The importance of 5-hydroxytryptamine receptors in the gut. Pharmacology and Therapeutics, 62, 159–173.PubMedCrossRefGoogle Scholar
  18. Spiegel, B. M., Gralnek, I. M., Bolus, R., Chang, L., Dulai, G. S., Mayer, E. A., et al. (2004). Clinical determinants of health-related quality of life in patients with irritable bowel syndrome. Archives of Internal Medicine, 164, 1773–1780.PubMedCrossRefGoogle Scholar
  19. Spiller, R., Aziz, Q., Creed, F., Emmanuel, A., Houghton, L., Hungin, P., Whorwell, P. (2007). Guidelines on the irritable bowel syndrome: mechanisms and practical management. Gut, 56(12), 1770–1798.PubMedPubMedCentralCrossRefGoogle Scholar
  20. Whitehead, W. E., Palsson, O., & Jones, K. R. (2002). Systematic review of the comorbidity of irritable bowel syndrome with others disorders: What are the causes and implications? Gastroenterology, 122, 1140–1156.PubMedCrossRefGoogle Scholar

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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of PsychiatryIndiana University School of MedicineIndianapolisUSA