A gene-environment (G-E) interaction refers to the susceptibility of genotypes to different environmental circumstances. In biometrical genetics, it is akin to a statistical interaction such that genetic effects on a phenotype vary as a function of the levels of an environmental variable.
References and Readings
- Donnelly, P. (2008). Progress and challenges in genome-wide association studies in humans. Nature Genetics, 456, 728–731.Google Scholar