Expanded Disability Status Scale
EDSS; Kurtzke expanded disability status scale
The Expanded Disability Status Scale (EDSS) is based upon the original Kurtzke Disability Status Scale (DSS) and Functional Systems (FS) (Kurtzke 1961). There are eight FSs: pyramidal, cerebellar, brainstem, sensory, visual, bowel and bladder, cerebral or mental, and other. Following neurological examination, each FS is rated on a scale of 0-5 (cerebellar and brainstem), 0-1 (other), and 0-6 (all others). These ratings assist in assigning an EDSS score which ranges from 0 to 10 in 0.5 increments, where 0 indicates a normal neurological examination (but cerebral grade 1 allowed) and 10 corresponds to death due to multiple sclerosis (MS) (see Kurtzke 1983for a full description of the rating scale). In general, EDSS scores ranging from 1.0 to 4.5 quantify the disability/impairment experienced by individuals with MS who are ambulatory, while EDSS scores from 5.0 to 9.5 correspond to disability/impairment of individuals...
References and Readings
- Bin Sawad, A., Seoane-Vazquez, E., Rodriguez-Monguio, R., & Turkistani, F. (2016). Evaluation of the expanded disability status scale and the multiple sclerosis functional composite as clinical endpoints in multiple sclerosis clinical trials: Quantitative meta-analyses. Current Medical Research and Opinion, 32, 1969–1974.PubMedCrossRefPubMedCentralGoogle Scholar
- Hobart, J. C., Lamping, D. L., Freeman, J. A., & Thompson, A. J. (1996). Reliability, validity and responsiveness of the Kurtzke expanded disability status scale (EDSS) in multiple sclerosis (MS) patients. European Journal of Neurology, 3(Suppl 4), 13.Google Scholar