Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan


  • John C. Courtney
  • Cristy Akins
  • Efrain Antonio GonzalezEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_1722

Generic Name


Brand Name

Effexor and Effexor XR


Antidepressants, serotonin norepinephrine reuptake inhibitors

Proposed Mechanism(s) of Action

Increases serotonin and norepinephrine by blocking both serotonin and norepinephrine reuptake pumps


Depression, generalized anxiety disorder, panic disorder, and social anxiety disorder

Off-Label Use

Post-traumatic stress disorder, ADHD, neuropathic pain, and premenstrual dysphoric disorder

Side Effects


Seizures, hypomania, and suicidal ideation


Hyponatremia, headache, nervousness, insomnia, sedation, nausea, diarrhea, appetite disturbance, sexual dysfunction, sweating, asthenia, and syndrome of inappropriate antidiuretic hormone secretion

References and Readings

  1. Physicians’ desk reference (71st ed.) (2017). Montvale: Thomson PDR.Google Scholar
  2. Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.Google Scholar

Additional Information

  1. Free drug online and PDA software. www.epocrates.com
  2. Free drug online and PDA software. www.medscape.com

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • John C. Courtney
    • 1
  • Cristy Akins
    • 2
  • Efrain Antonio Gonzalez
    • 3
    • 4
    Email author
  1. 1.Socorro Mental HealthPresbyterian Medical ServicesSocorroUSA
  2. 2.Mercy Family CenterMetarieUSA
  3. 3.College of PsychologyNova Southeastern UniversityFort LauderdaleUSA
  4. 4.Utah State UniversityLoganUSA