Generic Name
Tranlcypromine.
Brand Name
Parnate.
Class
Monoamine oxidase inhibitor (MAOI).
Proposed Mechanism(s) of Action
Inhibits the breakdown of norepinephrine, serotonin, and dopamine by irreversible/blocking the enzyme monoamine oxidase.
Indication
Major depressive disorder without melancholia.
Off-Label Use
Treatment-resistant depression, panic disorder, and social anxiety disorder.
Side Effects
Serious
Liver toxicity, hypertensive crisis, mania, suicidal ideation, and seizures.
Common
Orthostatic hypotension, sexual dysfunction, agitation, anxiety, insomnia, constipation, nausea, diarrhea, vomiting, dry mouth, appetite disturbance, and weight gain.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences and Readings
Physicians’ desk reference (71st ed.) (2017). Montvale: Thomson PDR.
Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York, NY: Cambridge University Press.
Additional Information
Drug Interaction Effects. http://www.drugs.com/drug_interactions.html.
Drug Molecule Images. http://www.worldofmolecules.com/drugs/.
Free Drug Online and PDA Software. www.epocrates.com.
Gene-Based Estimate of Drug interactions. http://mhc.daytondcs.com:8080/cgi bin/ddiD4?ver=4&task=getDrugList.
Pill Identification. http://www.drugs.com/pill_identification.html.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG, part of Springer Nature
About this entry
Cite this entry
Courtney, J.C., Akins, C., Gonzalez, E.A. (2018). Tranylcypromine. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_1716
Download citation
DOI: https://doi.org/10.1007/978-3-319-57111-9_1716
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-57110-2
Online ISBN: 978-3-319-57111-9
eBook Packages: Behavioral Science and PsychologyReference Module Humanities and Social SciencesReference Module Business, Economics and Social Sciences