Generic Name
Temazepam
Brand Name
Restoril
Class
Anxiolytics; sedative/hypnotics
Proposed Mechanism(s) of Action
Binds to benzodiazepine receptors at the GABA-A ligand-gated chloride channel. Inhibitor effects in sleep centers of the brain theoretically produce sedative effects.
Indication
Short-term treatment of insomnia
Off-Label Use
No common other use
Side Effects
Serious
Respiratory depression, rare hepatic and/or renal dysfunction, and blood dyscrasia
Common
Sedation, fatigue, memory problems, dizziness, slurred speech, disinhibition, anxiety, and rebound insomnia
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References and Readings
Physicians’ desk reference (71st ed.) (2017). Montvale: Thomson PDR.
Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.
Additional Information
Drug interaction effects. http://www.drugs.com/drug_interactions.html
Drug molecule images. http://www.worldofmolecules.com/drugs/
Free drug online and PDA software. www.epocrates.com
Free drug online and PDA software. www.medscape.com
Gene-based estimate of drug interactions. http://mhc.daytondcs.com:8080/cgi bin/ddiD4?ver=4&task=getDrugList
Pill identification. http://www.drugs.com/pill_identification.html
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Courtney, J.C., Gonzalez, E.A. (2018). Temazepam. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_1711
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DOI: https://doi.org/10.1007/978-3-319-57111-9_1711
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Online ISBN: 978-3-319-57111-9
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