Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan


  • John C. Courtney
  • Cristy Akins
  • Efrain Antonio GonzalezEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_1692

Generic Name


Brand Name

Nardil and Nardelzine


Antidepressants, monoamine oxidase inhibitors (MAOIs)

Proposed Mechanism(s) of Action

Reduces the breakdown of norepinephrine, serotonin, and dopamine via the inhibition of monoamine oxidase


Depression (atypical, nonendogenous, neurotic)

Off-Label Use

Treatment-resistant depression, panic disorder, and social anxiety disorder

Side Effects


Hypertensive crisis, seizures, liver toxicity, and mania


Orthostatic hypotension, syncope, sexual dysfunction, nausea, weight gain, blurred vision, dizziness, sedation, headache, sleep disturbance, tremor, weakness, and fatigue

References and Readings

  1. Physicians’ desk reference (71st ed.) (2017). Montvale: Thomson PDR.Google Scholar
  2. Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.Google Scholar

Additional Information

  1. Free Drug Online and PDA Software. www.epocrates.com
  2. Free Drug Online and PDA Software. www.medscape.com

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • John C. Courtney
    • 1
  • Cristy Akins
    • 2
  • Efrain Antonio Gonzalez
    • 3
    • 4
    Email author
  1. 1.Socorro Mental HealthPresbyterian Medical ServicesSocorroUSA
  2. 2.Mercy Family CenterMetarieUSA
  3. 3.College of PsychologyNova Southeastern UniversityFort LauderdaleUSA
  4. 4.Utah State UniversityLoganUSA