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Pentobarbital

  • Reference work entry
  • First Online:
Encyclopedia of Clinical Neuropsychology

  • 8 Accesses

Generic Name

Pentobarbital

Brand Name

Nembutal

Class

Barbiturates; sedative/hypnotics

Proposed Mechanism(s) of Action

Enhances effectiveness of GABA transmission and activates calcium channel

Indication

Seizures, preoperative sedation, and barbiturate coma

Off-Label Use

Reduction of intracranial pressure associated with Reye’s syndrome

Side Effects

Serious

Central nervous system depression, apnea, syncope, and death

Common

Agitation, ataxia, confusion, nervousness, insomnia, anxiety, dizziness, and hypotension

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References and Readings

  • Physicians’ desk reference (71st ed.) (2017). Montvale: Thomson PDR.

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  • Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.

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Author information

Authors and Affiliations

  1. Socorro Mental Health, Presbyterian Medical Services, Socorro, NM, USA

    John C. Courtney

  2. Mercy Family Center, Metairie, LA, USA

    Cristy Akins

  3. College of Psychology, Nova Southeastern University, Fort Lauderdale, FL, USA

    Efrain Antonio Gonzalez

  4. Utah State University, Logan, UT, USA

    Efrain Antonio Gonzalez

Authors
  1. John C. Courtney
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  2. Cristy Akins
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  3. Efrain Antonio Gonzalez
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Corresponding author

Correspondence to Efrain Antonio Gonzalez .

Editor information

Editors and Affiliations

  1. Department of Physical Medicine and Rehabilitation, Virginia Commonwealth University, Richmond, VA, USA

    Jeffrey S. Kreutzer

  2. Kessler Foundation, Pleasant Valley Way, West Orange, NJ, USA

    John DeLuca

  3. Independent Practice, Wynnewood, PA, USA

    Bruce Caplan

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© 2018 Springer International Publishing AG, part of Springer Nature

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Courtney, J.C., Akins, C., Gonzalez, E.A. (2018). Pentobarbital. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_1690

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