Generic Name
Mirtazapine
Brand Name
Remeron and Remeron Soltab
Class
Antidepressant
Proposed Mechanism(s) of Action
Alpha 2 antagonist (presynaptic autoreceptor antagonist), 5HT2a/c and 5HT3 antagonist, and antihistamine
Indication
Major depressive disorder
Off-Label Use
Panic disorder, generalized anxiety disorder, PTSD, and sedation
Side Effects
Somnolence, weight gain, xerostomia, increased appetite, and constipation
Serious
Seizures (rare), induction of mania (rare), and agranulocytosis (rare) activation of suicidal ideation (controversial)
Common
Dry mouth, constipation, increased appetite, weight gain, sedation, dizziness, abnormal dreams, and hypotension
References and Readings
Physicians’ desk reference (62nd ed.) (2007). Montvale: Thomson PDR.
Physicians’ desk reference (71st ed.) (2017). Montvale, NJ: Thomson PDR.
Additional Information
Drug Interaction Effects. http://www.drugs.com/drug_interactions.html
Drug Molecule Images. http://www.worldofmolecules.com/drugs/
Free Drug Online and PDA Software. www.epocrates.com
Gene-Based Estimate of Drug interactions. http://mhc.daytondcs.com:8080/cgi bin/ddiD4?ver=4&task=getDrugList
Pill Identification. http://www.drugs.com/pill_identification.html
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© 2018 Springer International Publishing AG, part of Springer Nature
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Courtney, J.C., Gonzalez, E.A. (2018). Mirtazapine. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_1677
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DOI: https://doi.org/10.1007/978-3-319-57111-9_1677
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Online ISBN: 978-3-319-57111-9
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