Generic Name
Haloperidol
Brand Name
Haldol
Class
Conventional antipsychotic
Proposed Mechanism(s) of Action
Blocks dopamine 2 receptors.
Indication
Psychotic disorders, Tourette’s syndrome (tics and vocal utterances), severe behavior problems, hyperactivity, and schizophrenia.
Off-Label Use
Bipolar disorder, behavioral disturbances related to dementia.
Side Effects
Anticholinergic effects, sedation, weight gain, erectile dysfunction, and oligomenorrhea or amenorrhea.
Serious
Agranulocytosis, seizures, leucopenia, and neuroleptic malignant syndrome.
Common
Akathisia, neuroleptic-induced deficit syndrome, extrapyramidal symptoms, galactorrhea, amenorrhea, dizziness, dry mouth, weight gain, and hypotension.
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References and Readings
Physicians’ Desk Reference (62nd ed.). (2007). Montvale: Thomson PDR.
Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.
Additional Information
Drug Interaction Effects: http://www.drugs.com/drug_interactions.html.
Drug Molecule Images: http://www.worldofmolecules.com/drugs/.
Free Drug Online and PDA Software: www.epocrates.com.
Gene-Based Estimate of Drug interactions: http://mhc.daytondcs.com:8080/cgibin/ddiD4?ver=4&task=getDrugList.
Pill Identification: http://www.drugs.com/pill_identification.html.
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Akins, C., Gonzalez, E.A. (2018). Haloperidol. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_1662
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DOI: https://doi.org/10.1007/978-3-319-57111-9_1662
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