Generic Name
Clonidine
Brand Name
Duraclon, Catapres, Catapres-TTS, Clorpres, Jenloga, Kapvay, Nexiclon XR
Class
Antihypertensive; alpha 2 agonists, central-acting; ADHD agents
Proposed Mechanism(s) of Action
Centrally acting alpha 2 agonist
Indication
Hypertension
Off-Label Use
Attention deficit hyperactivity disorder, Tourette’s syndrome, anxiety disorders including PTSD and social anxiety disorder, substance withdrawal including opiates and alcohol, smoking cessation, restless legs syndrome, Tourette’s syndrome, dysmenorrhea, postherpetic neuralgia, psychosis, pheochromocytoma, menopausal flushing, clonidine-induced hypersalivation, severe pain in cancer patients
Side Effects
Serious
Sinus bradycardia, atrioventricular block during withdrawal, hypertensive, encephalopathy, cerebrovascular accidents, and death
Common
Dry mouth, dizziness, constipation, sedation, major depression, weakness, fatigue, impotence, loss of libido, insomnia, headache, dermatologic reactions, hypotension,...
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Physicians’ desk reference (71st ed.) (2017). Montvale: Thomson PDR.
Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.
Additional Information
Drug Inter action Effects. http://www.drugs.com/drug_interactions.html
Drug Molecule Images. http://www.worldofmolecules.com/drugs/
Free Drug Online and PDA Software. www.epocrates.com
Free Drug Online and PDA Software. www.medscape.com
Gene-Based Estimate of Drug interactions. http://mhc.daytondcs.com:8080/cgi bin/ddiD4?ver=4&task=getDrugList
Pill Identification. http://www.drugs.com/pill_identification.html
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Courtney, J.C., Gonzalez, E.A. (2018). Clonidine. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_1641
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DOI: https://doi.org/10.1007/978-3-319-57111-9_1641
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Publisher Name: Springer, Cham
Print ISBN: 978-3-319-57110-2
Online ISBN: 978-3-319-57111-9
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