Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Chlordiazepoxide

  • John C. Courtney
  • Efrain Antonio GonzalezEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_1636

Generic Name

Chlordiazepoxide

Brand Name

Librium and Librax

Class

Antianxiety agents, anxiolytics, and benzodiazepines

Proposed Mechanism(s) of Action

Chlordiazepoxide binds to the GABA-A ligand-gated chloride channel complex and, thereby, enhances the inhibitory effects of GABA.

Indication

Anxiety disorders, symptoms of anxiety, preoperative apprehension and anxiety, and withdrawal from acute alcoholism

Side Effects

Serious

Respiratory depression, kidney dysfunction, and liver disorders (rare)

Common

Sedation, dizziness, depression, forgetfulness, confusion, and hyperexcitability

References and Readings

  1. Physicians’ desk reference (71st ed.). (2017). Montvale: Thomson PDR.Google Scholar
  2. Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.Google Scholar

Additional Information

  1. Free Drug Online and PDA Software. www.epocrates.com
  2. Free Drug Online and PDA Software. www.medscape.com

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Socorro Mental HealthPresbyterian Medical ServicesSocorroUSA
  2. 2.College of PsychologyNova Southeastern UniversityFort LauderdaleUSA
  3. 3.Utah State UniversityLoganUSA