Generic Name
Buspirone
Brand Name
BuSpar, Buspirex, Bustab, and Linbuspirone
Class
Antianxiety agents, anxiolytics, and nonbenzodiazepines
Proposed Mechanism(s) of Action
Serotonin 1A partial agonist, thus diminishing the overall serotonergic activity at those receptor sites.
Indication
Anxiety disorders.
Off-Label Use
Mixed anxiety and depression, treatment-resistant depression, and smoking cessation.
Side Effects
Serious
Very rare cardiac symptoms.
Common
Dizziness, sedation, nervousness, and nausea.
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References and Readings
Physicians’ Desk Reference (71st ed.). (2017). Montvale: Thomson PDR.
Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.
Additional Information
Drug Interaction Effects: http://www.drugs.com/drug_interactions.html.
Drug Molecule Images: http://www.worldofmolecules.com/drugs/.
Free Drug Online and PDA Software: www.epocrates.com.
Free Drug Online and PDA Software: www.medscape.com.
Gene-Based Estimate of Drug interactions: http://mhc.daytondcs.com:8080/cgibin/ddiD4?ver=4&task=getDrugList.
Pill Identification: http://www.drugs.com/pill_identification.html.
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Gonzalez, E.A. (2018). Buspirone. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_1634
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DOI: https://doi.org/10.1007/978-3-319-57111-9_1634
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