Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan


  • Efrain Antonio GonzalezEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_1634

Generic Name


Brand Name

BuSpar, Buspirex, Bustab, and Linbuspirone


Antianxiety agents, anxiolytics, and nonbenzodiazepines

Proposed Mechanism(s) of Action

Serotonin 1A partial agonist, thus diminishing the overall serotonergic activity at those receptor sites.


Anxiety disorders.

Off-Label Use

Mixed anxiety and depression, treatment-resistant depression, and smoking cessation.

Side Effects


Very rare cardiac symptoms.


Dizziness, sedation, nervousness, and nausea.

References and Readings

  1. Physicians’ Desk Reference (71st ed.). (2017). Montvale: Thomson PDR.Google Scholar
  2. Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.Google Scholar

Additional Information

  1. Free Drug Online and PDA Software: www.epocrates.com.
  2. Free Drug Online and PDA Software: www.medscape.com.

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.College of PsychologyNova Southeastern UniversityFort LauderdaleUSA
  2. 2.Utah State UniversityLoganUSA