Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Pilocytic Astrocytoma and Juvenile Pilocytic Astrocytoma

  • Jacqueline L. CunninghamEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_141

Synonyms

JPA; Juvenile pilocytic astrocytoma

Definition

The pilocytic astrocytoma, or juvenile pilocytic astrocytoma, is an intracranial tumor that results from the neoplastic proliferation of astrocytes, cells that are nonneural and serve as supportive cells of the nervous system. Astrocytic tumors are categorized into pilocytic and ordinary subtypes. Ordinary astrocytomas have a worse overall prognosis than the pilocytic because of their more aggressive behavior and their potential to undergo malignant transformation. The JPA occurs predominantly in children and young adults. It is the most common astrocytic tumor in children, accounting for 80–85% of cerebellar astrocytomas and 60% of optic gliomas. It is usually located in the cerebellum, brainstem, hypothalamic region, or optic pathways and can also occur in any area where astrocytes are present, including the cerebral hemispheres and the spinal cord. It is often cystic and if solid tends to be well circumscribed. Its presenting...
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References and Readings

  1. Keating, R. F., Goodrich, J. T., & Packer, R. J. (2001). Tumors of the pediatric central nervous system. New York: Thieme.CrossRefGoogle Scholar
  2. Sievert, A. J., & Fisher, M. J. (2009). Pediatric low-grade gliomas. Journal of Child Neurology, 24(11), 1397–1408.PubMedCentralCrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.College of PsychologyNova Southeastern UniversityFort LauderdaleUSA
  2. 2.Utah State UniversityLoganUSA