Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan


  • Christina KwasnicaEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_14


Split brain


The term referring to the medical procedure in which interconnecting fibers between the cerebral hemispheres are lesioned. The anatomic location includes either or both anterior and posterior fibers. When posterior fibers are resected, connections to the hippocampus may also be affected.

Current Knowledge

The neurosurgical technique is based on the premise that when stimuli enters the brain it is rapidly communicated via the corpus callosum to the other hemisphere. In refractory epilepsy, severing the corpus callosum may prevent the spread of electrical activity between hemispheres and generalization of the seizure activity. This procedure prevents the communication of the two hemispheres thus resulting in a clinical scenario of a “split brain.” Clinical disconnection syndromes in these patients have been studied across a large number of neurocognitive tasks. These surgical lesions have allowed for the study of sensory perceptual processes and...

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Further Readings

  1. Agrawal, D., Mohanty, B. B., Kumar, S., & Chinara, P. K. (2014). Split brain syndrome: One brain but two conscious minds? Journal of Health Research and Reviews, 1, 27–33.CrossRefGoogle Scholar
  2. Gazzaniga, M. S. (2000). Cerebral specialization and interhemispheric communication: Does the corpus callosum enable the human condition? Brain, 123, 1293–1213.PubMedCrossRefGoogle Scholar
  3. van der Knaap, L. J., & van der Ham, I. J. (2011). How does the corpus callosum mediate interhemispheric transfer? A review. Behavioural Brain Research, 223, 211–221.PubMedCrossRefGoogle Scholar
  4. Winter, T. J., & Franz, E. A. (2014). Implication of the anterior commissure in the allocation of attention to action. Frontiers in Psychology, 5, 432–435.PubMedPubMedCentralCrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Barrow Neurological InstitutePhoenixUSA