Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan


  • Farzin IraniEmail author
  • Anthony C. Ruocco
  • Lindsay C. Shima
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_1286


Psychotic misconception


A delusion is an erroneous belief typically associated with misinterpretation of perceptions or experiences. These beliefs are sustained despite incontrovertible evidence to the contrary. Delusions can occur in the context of a wide variety of psychiatric and medical conditions (for a review, see Fennig et al. 2005) including the following:
  • Psychiatric disorders such as psychotic disorders (schizophrenia, schizoaffective disorder, delusional disorder, brief psychotic disorder), mood disorders (bipolar disorder and depression), and substance-related disorders (amphetamines, cocaine, alcohol, cannabis, and hallucinogen)

  • Neurodegenerative disorders such as Alzheimer’s disease, frontotemporal dementia, dementia with Lewy bodies, Huntington’s disease, and multiple sclerosis

  • Other central nervous system disorders including brain tumors, particularly temporal lobe and deep hemispheric tumors, epilepsy, subdural hematomas, anoxic brain injuries, and...

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References and Readings

  1. American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: American Psychiatric Association.CrossRefGoogle Scholar
  2. Andreasen, N. (1984). Scale for the assessment of positive symptoms (SAPS). Iowa City: University of Iowa.Google Scholar
  3. Beards, S., & Fisher, H. L. (2014). The journey to psychosis: An exploration of specific psychological pathways. Social Psychiatry and Psychiatric Epidemiology, 49, 1541–1544.PubMedCrossRefPubMedCentralGoogle Scholar
  4. Blackwood, N., Howard, R., Bentall, R., & Murray, R. (2001). Cognitive neuropsychiatric models of persecutory delusions. American Journal of Psychiatry, 158, 527–539. [PubMed: 11282685].PubMedCrossRefPubMedCentralGoogle Scholar
  5. Bruen, P. D., McGeown, W. J., Shanks, M. F., & Venneri, A. (2008). Neuroanatomical correlates of neuropsychiatric symptoms in Alzheimer’s disease. Brain, 131, 2455–2463.PubMedCrossRefPubMedCentralGoogle Scholar
  6. Fennig, S., Fochtmann, L. J., & Bromet, E. J. (2005). Delusional and shared psychotic disorder. Kaplan & Sadock’s comprehensive textbook of psychiatry (8th ed.pp. 1525–1533). Philadelphia: Lippincott Williams & Wilkins.Google Scholar
  7. Freeman, D. (2007). Suspicious minds: The psychology of persecutory delusions. Clinical Psychology Review, 27, 425–457.PubMedCrossRefPubMedCentralGoogle Scholar
  8. Garety, P., & Freeman, D. (1999). Cognitive approaches to delusions: A critical review of theories and evidence. British Journal of Clinical Psychology, 38, 113–154.PubMedCrossRefPubMedCentralGoogle Scholar
  9. Garety, P. A., & Freeman, D. (2013). The past and future of delusions research: From the inexplicable to the treatable. The British Journal of Psychiatry, 203(5), 327–333.  https://doi.org/10.1192/bjp.bp.113.126953.CrossRefPubMedPubMedCentralGoogle Scholar
  10. Jerrell, J. M., & Ramirez, P. M. (2008). Changes in neuropsychological functioning following treatment with risperidone, olanzapine, and conventional antipsychotic medications. Human Psychopharmacology, 23, 595–604.PubMedCrossRefPubMedCentralGoogle Scholar
  11. Kim, D. K., Kim, B. L., Sohn, S. E., Lim, S. W., Na, D. G., et al. (1999). Candidate neuroanatomic substrates of psychosis in old-aged depression. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 23, 793–807.PubMedCrossRefPubMedCentralGoogle Scholar
  12. Maj, M., Pirozzi, R., Magliano, L., Fiorillo, A., & Bartoli, L. (2007). Phenomenology and prognostic significance of delusions in major depressive disorder: A 10-year prospective follow-up study. Journal of Clinical Psychiatry, 68, 1411–1417.PubMedCrossRefPubMedCentralGoogle Scholar
  13. Mancevski, B., Keilp, J., Kurzon, M., Berman, R. M., Ortakov, V., et al. (2007). Lifelong course of positive and negative symptoms in chronically institutionalized patients with schizophrenia. Psychopathology, 40, 83–92.PubMedCrossRefPubMedCentralGoogle Scholar
  14. Nomura, K., Kazui, H., Wada, T., Sugiyama, H., Yamamoto, D., Yoshiyama, K., Shimosegawa, E., Hatazawa, J., & Takeda, M. (2013). Classification of delusions in Alzheimer’s disease and their neural correlates. Psychogeriatrics, 12, 200–210.CrossRefGoogle Scholar
  15. O’Leary, D. S., Flaum, M., Kesler, M. L., Flashman, L. A., Arndt, S., et al. (2000). Cognitive correlates of the negative, disorganized, and psychotic symptom dimensions of schizophrenia. Journal of Neuropsychiatry and Clinical Neurosciences, 12, 4–15.PubMedCrossRefPubMedCentralGoogle Scholar
  16. Peters, E., Joseph, S., Day, S., & Garety, P. (2004). Measuring delusional ideation: The 21-item Peters et al. Delusions Inventory (PDI). Schizophrenia Bulletin, 30(4), 1005.PubMedCrossRefPubMedCentralGoogle Scholar
  17. Rathod, S., Kingdon, D., Weiden, P., & Turkington, D. (2008). Cognitive-behavioral therapy for medication-resistant schizophrenia: A review. Journal of Psychiatric Practice, 14, 22–33.PubMedCrossRefPubMedCentralGoogle Scholar
  18. Sartorius, N., Jablensky, A., Korten, A., Ernberg, G., Anker, M., et al. (1986). Early manifestations and first-contact incidence of schizophrenia in different cultures. A preliminary report on the initial evaluation phase of the WHO Collaborative Study on determinants of outcome of severe mental disorders. Psychological Medicine, 16, 909–928.PubMedCrossRefPubMedCentralGoogle Scholar
  19. Stevens, J. R. (1992). Abnormal reinnervation as a basis for schizophrenia: A hypothesis. Archives of General Psychiatry, 49, 238–243.PubMedCrossRefPubMedCentralGoogle Scholar
  20. Tascone, L., & Bottino, C. (2013). Neurobiology of neuropsychiatric symptoms in Alzheimer’s disease: A critical review with a focus on neuroimaging. Dementia Neuropsychology, 7, 236–243.CrossRefGoogle Scholar
  21. Thomas, N., Shawyer, F., Castle, D. J., Copolov, D., Hayes, S. C., & Farhall, J. (2014). A randomised controlled trial of acceptance and commitment therapy (ACT) for psychosis: Study protocol. BMC Psychiatry, 14, 198.PubMedPubMedCentralCrossRefGoogle Scholar
  22. Woodward, T. S., Jung, K., Hwang, H., Yin, J., Taylor, L., Menon, M., ..., & Sommer, I. E. (2014). Symptom dimensions of the psychotic symptom rating scales in psychosis: A multisite study. Schizophrenia Bulletin, 40(Suppl 4), S265–S274.PubMedPubMedCentralCrossRefGoogle Scholar
  23. Yamasaki, S., Yamasue, H., Abe, O., Yamada, H., Iwanami, A., et al. (2007). Reduced planum temporale volume and delusional behaviour in patients with schizophrenia. European Archives of Psychiatry and Clinical Neuroscience, 257, 318–324.PubMedCrossRefPubMedCentralGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Farzin Irani
    • 1
    Email author
  • Anthony C. Ruocco
    • 2
  • Lindsay C. Shima
    • 3
  1. 1.Psychology DepartmentWest Chester University of PennsylvaniaWest ChesterUSA
  2. 2.Department of PsychologyUniversity of TorontoTorontoCanada
  3. 3.Department of Psychology, Neuropsychology Research GroupWest Chester University of PennsylvaniaWest ChesterUSA