Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Hemangiopericytoma

  • Jennifer TinkerEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_117

Definition

A hemangiopericytoma (HPC) is a highly vascularized soft tissue neoplasm arising from pericytes (connective tissue cells) encapsulating capillaries and postcapillary venules. CNS hemangiopericytomas are almost exclusively found to occur within the epidural space of the brain and spinal cord, without infiltrating the surrounding CNS parenchyma. Approximately 70% are supratentorial, with 15% in the posterior fossa and 15% in the spinal cord. Intraventricular lesions have also been reported (Al-Brahim et al. 2004). Duration of symptoms at presentation is typically less than 1 year due to rapid growth. Most common presenting complaint is headache, focal neurological deficit, and/or seizure. Hemangiopericytomas are particularly aggressive tumors that have high rates of metastasis and a tendency to recur, even following gross total resection, which is the principal treatment strategy (32–67% of published cases). Although these tumors are extra-axial, they can cause limited...

This is a preview of subscription content, log in to check access.

References and Readings

  1. Al-Brahim, N., Devilliers, R., & Provias, J. (2004). Intraventricular hemangiopericytoma. Annals of Diagnostic Pathology, 8(6), 347–351.PubMedCrossRefGoogle Scholar
  2. Ecker, R. D., Marsh, W. R., Pollock, B. E., Kurtkaya-Yapicier, O., McClelland, R., Scheithauer, B. W., et al. (2003). Hemangiopericytoma in the central nervous system: Treatment, pathological features, and long-term follow up in 38 patients. Journal of Neurosurgery, 98, 1182–1187.PubMedCrossRefGoogle Scholar
  3. Park, M. S., & Araujo, D. M. (2009). New insights into the hemangiopericytoma/solitary fibrous tumor spectrum of tumors. Current Opinion in Oncology, 21(4), 327–331.PubMedCrossRefGoogle Scholar
  4. Rutkowski, M. J., Jian, B. J., Bloch, O., Chen, C., Sughrue, M. E., Tihan, T., Barani, I. J., Berger, M. S., McDermott, M. W., & Parsa, A. T. (2012). Intracranial hemangiopericytoma: Clinical experience and treatment considerations in a modern series of 40 adult patients. Cancer, 118(6), 1628–1636.PubMedCrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of NeurologyThomas Jefferson UniversityPhiladelphiaUSA