Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Craniopharyngioma

  • Ethan MoitraEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_100

Definition

Craniopharyngioma is a slow-growing, extra-axial, epithelial-squamous, calcified cystic tumor that develops near the pituitary gland. It occupies the suprasellar/sellar region and shows benign histology but malignant behavior, as it may invade surrounding areas and recur after treatment (Fahlbusch et al. 1999). Craniopharyngiomas may develop embryogenetically, arising from remnants of the craniopharyngeal duct and/or Rathke cleft, or metaplastically because of residual squamous epithelium. The most common presenting symptoms are endocrine dysfunction, headache, and visual disturbances. Craniopharyngiomas are treated with surgical excision or surgery followed by radiotherapy (Fig. 1).
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References and Readings

  1. Fahlbusch, R., Honegger, J., Paulus, W., Huk, W., & Buchfelder, M. (1999). Surgical treatment of craniopharyngiomas: Experience with 168 patients. Journal of Neurosurgery, 90, 237–250.PubMedCrossRefPubMedCentralGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Psychiatry and Human BehaviorBrown UniversityProvidenceUSA