Encyclopedia of Clinical Neuropsychology

Living Edition
| Editors: Jeffrey Kreutzer, John DeLuca, Bruce Caplan

Dementia with Lewy Bodies

  • Matthew Kraybill
  • Yana Suchy
Living reference work entry
DOI: https://doi.org/10.1007/978-3-319-56782-2_502-2



Dementia with Lewy bodies (DLB) is part of a spectrum of neurodegenerative disorders associated with dysregulation and aggregation of alpha-synuclein (McKeith 2006). DLB is characterized by progressive cognitive decline combined with three additional defining features: (1) pronounced fluctuations in alertness and attention (e.g., frequent drowsiness, lethargy, and disorganized speech), (2) visual hallucinations, and (3) parkinsonian motor symptoms (e.g., resting tremor, muscle rigidity, bradykinesia, and/or postural instability) (see Table 1; McKeith et al. 1996, 2005).
Table 1

Revised criteria for the clinical diagnosis of probable or possible DLB (Adapted from McKeith et al. (2005))

Central features

Core features

Suggestive features

Supportive features


Progressive dementia with impairments in (a) memory, (b) attention, (c) executive...


Dementia With Lewy Bodies (DLB) McKeith Diffuse Lewy Body Disease (DLBD) Autopsy-confirmed Cases Extrapyramidal Motor Features 
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References and Readings

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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  • Matthew Kraybill
    • 1
  • Yana Suchy
    • 2
  1. 1.NeuropsychologyCottage Rehabilitation HospitalSanta BarbaraUSA
  2. 2.Department of PsychologyUniversity of UtahSalt Lake CityUSA