- 31 Downloads
Multi-infarct dementia is a vascular dementia syndrome characterized by cognitive decline resulting from the combined effects of multiple ischemic lesions in the brain. Ischemic lesions include large and small cortical and subcortical infarcts, lacunar infarcts, and diffuse white matter ischemic changes. This particular subtype of vascular dementia, in which multiple infarcts (i.e., dead tissue areas) are present, is contrasted with cognitive impairment caused by other forms of cerebrovascular change (i.e., small vessel dementia, hemorrhagic cerebrovascular dementia, strategic infarct dementia, etc.).
The term multi-infarct dementia, coined by Hachinski in 1974, was initially used to describe dementia due to vascular pathology. In 1985, Loeb introduced the term vascular dementia to refer to a global class...
References and Readings
- Goetz, C. G. (2007). Textbook of clinical neurology (3rd ed.). Philadelphia: Saunders.Google Scholar
- Moore, D. P., & Jefferson, J. W. (2004). Handbook of medical psychiatry (2nd ed.). Philadelphia: Mosby.Google Scholar
- Smith, G. E., & Bondi, M. W. (2013). Mild cognitive impairment and dementia. New York: Oxford University Press.Google Scholar